Oral Presentation Australian and New Zealand Stroke Organisation Conference 2026

Investigating grief as a distinct emotional response after stroke. (139263)

Katherine Sewell 1 2 , Serena Alves-Stein 1 2 , Zhibin Chen 1 , Leo Chen 3 4 , Natasha Lannin 1 2
  1. Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia
  2. Bayside Health, Melbourne, Australia
  3. Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
  4. Mental Health and Addiction Medicine, St Vincent’s Hospital, Melbourne, Victoria, Australia

Background/aims:
Grief after stroke is largely overlooked in both research and clinical practice. Sudden loss of independence, roles, identity, and future may precipitate a distinct form of grief. Although related to depression, evidence from non-stroke populations suggests that grief and depression are distinct conditions requiring different management. This study examined the association between depressive symptoms and grief post-stroke.
Methods:
We conducted an observational cohort study of stroke survivors from two rehabilitation centres in Victoria and South Australia. Participants completed the Spinal Cord Injury—Quality of Life (SCI-QoL) Grief and Loss measure adapted for stroke, and the Hospital Anxiety and Depression Scale (HADS) between 1–12 months post-stroke. Associations between grief and depressive symptoms were analysed using Spearman’s correlation, Mann–Whitney U, and Fisher’s exact tests.
Results:
Thirty-two stroke survivors were included (18 [56%] male; median age 56 years, IQR 45.5–62.5). Most had ischaemic stroke (n=26, 81%). Ten (31%) reported clinically significant depressive symptoms (HADS-D≥8) and 14 (44%) had elevated grief (SCI-QoL T-scores above the SCI population mean). Depression and grief scores were positively associated (Spearman ρ=0.58, p<0.001). Participants with depressive symptoms had higher grief scores (median 55.9, IQR 10.7) than those without (median 46.2, IQR 12; p<0.003). Grief frequently co-occurred with depression (8/10 cases) but also occurred in participants without depression (5/22, p=0.005).
Conclusion:
Grief was common post-stroke and occurred both with and without depression, highlighting grief as a distinct and clinically relevant aspect of post-stroke recovery. These findings support further research into post-stroke grief and suggest potential clinical implications, including tailored management strategies.