Lightning Oral Presentation Australian and New Zealand Stroke Organisation Conference 2026

StTop: Stroke thrombolysis time out procedure: a safety step to empower code stroke nursing teams (139580)

Shona Haigh 1 , Suzanne Sheppard-Law 2 , Melissa Heazlewood 3 , Stephanie Barber 4 , Donna Kylstra 5 , Melinda Johnson 6 , Emma Richards 7 , Briony Van Galen 1 , Ken Butcher 8 , Sanjoy Talukdar 9
  1. NSW Telestroke Service, Randwick
  2. University of Technology Sydney, Sydney
  3. Wagga Wagga Base Hospital, Wagga Wagga
  4. Port Macquarie Base Hospital, Port Macquarie
  5. Lismore Base Hospital, Lismore
  6. Tweed Valley Hospital, Tweed
  7. Coffs Harbour Health Service, Coffs Harbour
  8. Prince of Wales Clinical School, University of New South Wales, Clinical Neurosciences, Randwick
  9. NSW Telestroke Service, Prince of Wales Hospital, Randwick

Background/Aims

Stroke thrombolysis requires precise time-critical administration to be safe and effective. Safety time-outs in stroke thrombolysis are underutilised. A multidisciplinary stroke thrombolysis ‘time-out’ was implemented at NSW Telestroke referral sites. This research evaluated the efficacy and safety of the Stroke Thrombolysis Time-Out Procedure (StToP) utilised by code stroke teams.

 

Methods

We conducted a comparative pre and post-implementation evaluation, using cross-sectional surveys to measure nursing perceptions of safety, communication and efficacy (7-point Likert scale) during thrombolysis in acute ischaemic stroke. Retrospective and prospective ‘door-to-needle’ time data are collected to ensure efficiency of process without delay. The StTop education, including professional video, and protocol were developed and implemented in 2025. Five regional NSW Telestroke referral sites were recruited with 40 participants pre-intervention and 12 post-intervention, survey collection ongoing.

 

Results

The StToP initiative was performed in 34/36 (94%) of acute stroke thrombolysis cases. The median door-to-needle time in the pre-intervention group (n=45) was 48 minutes (IQR 38–65) and 46 minutes (IQR 38–66) in the post-intervention group (n=39) exceeding national targets (<60 minutes). Pre-to-post improvement in team communication was identified, specifically the ability to ask questions within the team according to current data (pre: 51%, post: 91%), and input acknowledgment (pre: 45%, post: 83%). 12/12 (100%) of respondents agreed the StTop improved patient safety, supported a culture of safety, whilst allowing for timely thrombolysis.